Inflammatory signaling regulates embryonic hematopoietic stem and progenitor cell production

Identifying signaling pathways that regulate hematopoietic stem and progenitor cell (HSPC) formation in the embryo will guide efforts to produce and expand HSPCs ex vivo. Here we show that sterile tonic inflammatory signaling regulates embryonic HSPC formation. Expression profiling of progenitors wi...

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Bibliografiske detaljer
Udgivet i:Genes Dev
Main Authors: Li, Yan, Esain, Virginie, Teng, Li, Xu, Jian, Kwan, Wanda, Frost, Isaura M., Yzaguirre, Amanda D., Cai, Xiongwei, Cortes, Mauricio, Maijenburg, Marijke W., Tober, Joanna, Dzierzak, Elaine, Orkin, Stuart H., Tan, Kai, North, Trista E., Speck, Nancy A.
Format: Artigo
Sprog:Inglês
Udgivet: Cold Spring Harbor Laboratory Press 2014
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4248291/
https://ncbi.nlm.nih.gov/pubmed/25395663
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.253302.114
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