Inflammatory signaling regulates embryonic hematopoietic stem and progenitor cell production

Identifying signaling pathways that regulate hematopoietic stem and progenitor cell (HSPC) formation in the embryo will guide efforts to produce and expand HSPCs ex vivo. Here we show that sterile tonic inflammatory signaling regulates embryonic HSPC formation. Expression profiling of progenitors wi...

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Detalles Bibliográficos
Publicado en:Genes Dev
Main Authors: Li, Yan, Esain, Virginie, Teng, Li, Xu, Jian, Kwan, Wanda, Frost, Isaura M., Yzaguirre, Amanda D., Cai, Xiongwei, Cortes, Mauricio, Maijenburg, Marijke W., Tober, Joanna, Dzierzak, Elaine, Orkin, Stuart H., Tan, Kai, North, Trista E., Speck, Nancy A.
Formato: Artigo
Idioma:Inglês
Publicado: Cold Spring Harbor Laboratory Press 2014
Assuntos:
Research Paper
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4248291/
https://ncbi.nlm.nih.gov/pubmed/25395663
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.253302.114
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