Inflammatory signaling regulates embryonic hematopoietic stem and progenitor cell production

Identifying signaling pathways that regulate hematopoietic stem and progenitor cell (HSPC) formation in the embryo will guide efforts to produce and expand HSPCs ex vivo. Here we show that sterile tonic inflammatory signaling regulates embryonic HSPC formation. Expression profiling of progenitors wi...

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Publicat a:Genes Dev
Autors principals: Li, Yan, Esain, Virginie, Teng, Li, Xu, Jian, Kwan, Wanda, Frost, Isaura M., Yzaguirre, Amanda D., Cai, Xiongwei, Cortes, Mauricio, Maijenburg, Marijke W., Tober, Joanna, Dzierzak, Elaine, Orkin, Stuart H., Tan, Kai, North, Trista E., Speck, Nancy A.
Format: Artigo
Idioma:Inglês
Publicat: Cold Spring Harbor Laboratory Press 2014
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4248291/
https://ncbi.nlm.nih.gov/pubmed/25395663
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.253302.114
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