Central Nervous System Regulation of Embryonic HSPC Production via Stress-Responsive Glucocorticoid Receptor Signaling

Hematopoietic stem and progenitor cell (HSPC) specification is regulated by numerous defined factors acting locally within the hemogenic niche, however, it is unclear whether production can adapt to fluctuating systemic needs. Here, we show the central nervous system controls embryonic HSPC producti...

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Bibliografiset tiedot
Julkaisussa:Cell Stem Cell
Päätekijät: Kwan, Wanda, Cortes, Mauricio, Frost, Isaura, Esain, Virginie, Theodore, Lindsay N., Liu, Sarah Y., Budrow, Nadine, Goessling, Wolfram, North, Trista E.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2016
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5181112/
https://ncbi.nlm.nih.gov/pubmed/27424782
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2016.06.004
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