Central Nervous System Regulation of Embryonic HSPC Production via Stress-Responsive Glucocorticoid Receptor Signaling

Hematopoietic stem and progenitor cell (HSPC) specification is regulated by numerous defined factors acting locally within the hemogenic niche, however, it is unclear whether production can adapt to fluctuating systemic needs. Here, we show the central nervous system controls embryonic HSPC producti...

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Bibliografiske detaljer
Udgivet i:Cell Stem Cell
Main Authors: Kwan, Wanda, Cortes, Mauricio, Frost, Isaura, Esain, Virginie, Theodore, Lindsay N., Liu, Sarah Y., Budrow, Nadine, Goessling, Wolfram, North, Trista E.
Format: Artigo
Sprog:Inglês
Udgivet: 2016
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5181112/
https://ncbi.nlm.nih.gov/pubmed/27424782
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2016.06.004
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