Cannabinoid Receptor-2 Regulates Embryonic Hematopoietic Stem Cell Development via Prostaglandin E2 and P-Selectin Activity

Cannabinoids (CB) modulate adult hematopoietic stem and progenitor cell (HSPCs) function, however, impact on the production, expansion, or migration of embryonic HSCs is currently uncharacterized. Here, using chemical and genetic approaches targeting CB-signaling in zebrafish, we show that CB recept...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Stem Cells
Egile Nagusiak: Esain, Virginie, Kwan, Wanda, Carroll, Kelli J., Cortes, Mauricio, Liu, Sarah Y., Frechette, Gregory M., Sheward, Lea M. V., Nissim, Sahar, Goessling, Wolfram, North, Trista E.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2015
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4781665/
https://ncbi.nlm.nih.gov/pubmed/25931248
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/stem.2044
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