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Cannabinoid Receptor-2 Regulates Embryonic Hematopoietic Stem Cell Development via Prostaglandin E2 and P-Selectin Activity

Cannabinoids (CB) modulate adult hematopoietic stem and progenitor cell (HSPCs) function, however, impact on the production, expansion, or migration of embryonic HSCs is currently uncharacterized. Here, using chemical and genetic approaches targeting CB-signaling in zebrafish, we show that CB recept...

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Bibliografiset tiedot
Julkaisussa:Stem Cells
Päätekijät: Esain, Virginie, Kwan, Wanda, Carroll, Kelli J., Cortes, Mauricio, Liu, Sarah Y., Frechette, Gregory M., Sheward, Lea M. V., Nissim, Sahar, Goessling, Wolfram, North, Trista E.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2015
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4781665/
https://ncbi.nlm.nih.gov/pubmed/25931248
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/stem.2044
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