Estrogen Defines the Dorsal-Ventral Limit of VEGF Regulation to Specify the Location of the Hemogenic Endothelial Niche

The genetic control of hematopoietic stem and progenitor cell (HSPC) function is increasingly understood, however less is known about the interactions specifying the embryonic hematopoietic niche. Here, we report 17β-estradiol (E2) influences the production of runx1+ HSPCs in the AGM region by antag...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Dev Cell
Prif Awduron: Carroll, Kelli J, Esain, Virginie, Garnaas, Maija K, Cortes, Mauricio, Dovey, Michael C, Nissim, Sahar, Frechette, Gregory, Liu, Sarah, Kwan, Wanda, Cutting, Claire C, Harris, James M, Gorelick, Daniel, Halpern, Marnie, Lawson, Nathan, Goessling, Wolfram, North, Trista E
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2014
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4469361/
https://ncbi.nlm.nih.gov/pubmed/24871948
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2014.04.012
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