Estrogen Defines the Dorsal-Ventral Limit of VEGF Regulation to Specify the Location of the Hemogenic Endothelial Niche

The genetic control of hematopoietic stem and progenitor cell (HSPC) function is increasingly understood, however less is known about the interactions specifying the embryonic hematopoietic niche. Here, we report 17β-estradiol (E2) influences the production of runx1+ HSPCs in the AGM region by antag...

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Detalhes bibliográficos
Publicado no:Dev Cell
Main Authors: Carroll, Kelli J, Esain, Virginie, Garnaas, Maija K, Cortes, Mauricio, Dovey, Michael C, Nissim, Sahar, Frechette, Gregory, Liu, Sarah, Kwan, Wanda, Cutting, Claire C, Harris, James M, Gorelick, Daniel, Halpern, Marnie, Lawson, Nathan, Goessling, Wolfram, North, Trista E
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4469361/
https://ncbi.nlm.nih.gov/pubmed/24871948
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2014.04.012
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