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Evi1 regulates Notch activation to induce zebrafish hematopoietic stem cell emergence

During development, hematopoietic stem cells (HSCs) emerge from aortic endothelial cells (ECs) through an intermediate stage called hemogenic endothelium by a process known as endothelial‐to‐hematopoietic transition (EHT). While Notch signaling, including its upstream regulator Vegf, is known to reg...

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Bibliografische gegevens
Gepubliceerd in:EMBO J
Hoofdauteurs: Konantz, Martina, Alghisi, Elisa, Müller, Joëlle S, Lenard, Anna, Esain, Virginie, Carroll, Kelli J, Kanz, Lothar, North, Trista E, Lengerke, Claudia
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: John Wiley and Sons Inc. 2016
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5090218/
https://ncbi.nlm.nih.gov/pubmed/27638855
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201593454
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