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Evi1 regulates Notch activation to induce zebrafish hematopoietic stem cell emergence

During development, hematopoietic stem cells (HSCs) emerge from aortic endothelial cells (ECs) through an intermediate stage called hemogenic endothelium by a process known as endothelial‐to‐hematopoietic transition (EHT). While Notch signaling, including its upstream regulator Vegf, is known to reg...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:EMBO J
Main Authors: Konantz, Martina, Alghisi, Elisa, Müller, Joëlle S, Lenard, Anna, Esain, Virginie, Carroll, Kelli J, Kanz, Lothar, North, Trista E, Lengerke, Claudia
Format: Artigo
Jezik:Inglês
Izdano: John Wiley and Sons Inc. 2016
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5090218/
https://ncbi.nlm.nih.gov/pubmed/27638855
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201593454
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