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Evi1 regulates Notch activation to induce zebrafish hematopoietic stem cell emergence
During development, hematopoietic stem cells (HSCs) emerge from aortic endothelial cells (ECs) through an intermediate stage called hemogenic endothelium by a process known as endothelial‐to‐hematopoietic transition (EHT). While Notch signaling, including its upstream regulator Vegf, is known to reg...
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| Опубликовано в: : | EMBO J |
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| Главные авторы: | , , , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
John Wiley and Sons Inc.
2016
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5090218/ https://ncbi.nlm.nih.gov/pubmed/27638855 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201593454 |
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