Metabolic regulation of inflammasome activity controls embryonic hematopoietic stem and progenitor cell production

Embryonic hematopoietic stem and progenitor cells (HSPCs) robustly proliferate while maintaining multilineage potential in vivo; however, an incomplete understanding of spatiotemporal cues governing their generation has impeded robust production from human induced pluripotent stem cells (iPSCs) in v...

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Detalhes bibliográficos
Publicado no:Dev Cell
Main Authors: Frame, Jenna M., Kubaczka, Caroline, Long, Timothy L., Esain, Virginie, Soto, Rebecca A., Hachimi, Mariam, Jing, Ran, Shwartz, Arkadi, Goessling, Wolfram, Daley, George Q., North, Trista E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8008739/
https://ncbi.nlm.nih.gov/pubmed/32810442
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2020.07.015
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