Systemic oxygenation weakens the hypoxia and Hypoxia Inducible Factor 1α-dependent and extracellular adenosine-mediated tumor protection

Intratumoral hypoxia and Hypoxia Inducible Factor-1α (HIF-1α)-dependent CD39/CD73 ecto-enzymes may govern the accumulation of tumor-protecting extracellular adenosine and signaling through the A2A adenosine receptors (A2AR) in tumor microenvironments (TME). Here, we explored the conceptually novel m...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:J Mol Med (Berl)
Main Authors: Hatfield, Stephen M., Kjaergaard, Jorgen, Lukashev, Dmitriy, Belikoff, Bryan, Schreiber, Taylor H., Sethumadhavan, Shalini, Abbott, Robert, Philbrook, Phaethon, Thayer, Molly, Shujia, Dai, Rodig, Scott, Kutok, Jeffrey L., Ren, Jin, Ohta, Akio, Podack, Eckhard R., Karger, Barry, Jackson, Edwin K., Sitkovsky, Michail
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4247798/
https://ncbi.nlm.nih.gov/pubmed/25120128
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00109-014-1189-3
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados