A Metabolic Immune Checkpoint: Adenosine in Tumor Microenvironment

por Ohta, Akio
Publicado en Front Immunol (2016)

The adenosinergic immuno-modulatory drugs

por Ohta, Akio, Sitkovsky, Michail
Publicado 2009

Targeting the hypoxia-adenosinergic signaling pathway to improve the adoptive immunotherapy of cancer

por Sitkovsky, Michail, Ohta, Akio
Publicado 2013

Extracellular Adenosine-Mediated Modulation of Regulatory T Cells

por Ohta, Akio, Sitkovsky, Michail
Publicado 2014

From ‘Hellstrom Paradox–to anti-adenosinergic cancer immunotherapy

por Lukashev, Dmitriy, Sitkovsky, Michail, Ohta, Akio
Publicado 2007

Effect of Ezetimibe Monotherapy on Low-Density Lipoprotein Cholesterol and on Markers of Cholesterol Synthesis and Absorption in Japanese Patients With Hypercholesterolemia

por Ohta, Akio, Kato, Hiroyuki, Ishii, Satoshi, Nagai, Yoshio, Tanaka, Yasushi
Publicado en J Clin Med Res (2017)

A(2A) adenosine receptor gene-deletion or synthetic A(2A) antagonist liberate tumor-reactive CD8(+) T-cells from tumor-induced immunosuppression

por Kjaergaard, Jorgen, Hatfield, Stephen, Jones, Graham, Ohta, Akio, Sitkovsky, Michail
Publicado en J Immunol (2018)

The antihypoxia–adenosinergic pathogenesis as a result of collateral damage by overactive immune cells

por Hatfield, Stephen, Belikoff, Bryan, Lukashev, Dmitriy, Sitkovsky, Michail, Ohta, Akio
Publicado en J Leukoc Biol (2009)

In vivo T Cell Activation in Lymphoid Tissues is Inhibited in the Oxygen-Poor Microenvironment

por Ohta, Akio, Diwanji, Rohan, Kini, Radhika, Subramanian, Meenakshi, Ohta, Akiko, Sitkovsky, Michail
Publicado 2011

The development and immunosuppressive functions of CD4(+) CD25(+) FoxP3(+) regulatory T cells are under influence of the adenosine-A2A adenosine receptor pathway

por Ohta, Akio, Kini, Radhika, Ohta, Akiko, Subramanian, Meenakshi, Madasu, Manasa, Sitkovsky, Michail
Publicado 2012

Differing Effect of the Sodium-Glucose Cotransporter 2 Inhibitor Ipragliflozin on the Decrease of Fat Mass vs. Lean Mass in Patients With or Without Metformin Therapy

por Nagai, Yoshio, Fukuda, Hisashi, Kawanabe, Shin, Nakagawa, Tomoko, Ohta, Akio, Tanaka, Yasushi
Publicado en J Clin Med Res (2019)

Hostile, Hypoxia-A2-Adenosinergic Tumor Biology as the Next Barrier to the Tumor Immunologists

por Sitkovsky, Michail V., Hatfield, Stephen, Abbott, Robert, Belikoff, Bryan, Lukashev, Dmitry, Ohta, Akio
Publicado en Cancer Immunol Res (2014)

Genetic deletion of the alternative isoform I.1 of HIF-1α in T cells enhances anti-bacterial immune response and improves survival in the model of bacterial peritonitis in mice

por Georgiev, Peter, Belikoff, Bryan B., Hatfield, Stephen, Ohta, Akio, Sitkovsky, Michail V., Lukashev, Dmitry
Publicado 2013

Short-term change of carotid intima-media thickness after treatment of hyperglycemia in patients with diabetes: a cross-sectional study

por Tenjin, Ayumi, Nagai, Yoshio, Yuji, Sayaka, Ishii, Satoshi, Kato, Hiroyuki, Ohta, Akio, Tanaka, Yasushi
Publicado en BMC Res Notes (2016)

Prenatal and Postnatal Epigenetic Programming: Implications for GI, Immune, and Neuronal Function in Autism

por Waly, Mostafa I., Hornig, Mady, Trivedi, Malav, Hodgson, Nathaniel, Kini, Radhika, Ohta, Akio, Deth, Richard
Publicado 2012

Inactivation of the PD-1-Dependent Immunoregulation in Mice Exacerbates Contact Hypersensitivity Resembling Immune-Related Adverse Events

por Ashoori, Matin Dokht, Suzuki, Kensuke, Tokumaru, Yosuke, Ikuta, Naoko, Tajima, Masaki, Honjo, Tasuku, Ohta, Akio
Publicado en Front Immunol (2021)

The A2aR adenosine receptor controls cytokine production in iNKT cells

por Nowak, Michael, Lynch, Lydia, Yue, Simon, Ohta, Akio, Sitkovsky, Michail, Balk, Steven P., Exley, Mark. A.
Publicado 2010

Hypoxia-induced and A2A adenosine receptor-independent T-cell suppression is short lived and easily reversible

por Ohta, Akio, Madasu, Manasa, Subramanian, Meenakshi, Kini, Radhika, Jones, Graham, Choukèr, Alexander, Ohta, Akiko, Sitkovsky, Michail
Publicado 2014

Comparison of daily glucose excursion by continuous glucose monitoring between type 2 diabetic patients receiving biphasic insulin aspart 30 or biphasic human insulin 30

por Ohta, Akio, Suwa, Tomoko, Sada, Yoshiyuki, Kato, Hiroyuki, Koganei, Rieko, Asai, Shikou, Katabami, Takuyuki, Tanaka, Yasushi
Publicado 2011

Physiological control of NKT cell-dependent hepatitis induction by extracellular adenosine

por Subramanian, Meenakshi, Kini, Radhika, Madasu, Manasa, Ohta, Akiko, Nowak, Michael, Exley, Mark, Sitkovsky, Michail, Ohta, Akio
Publicado en Eur J Immunol (2014)