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A Metabolic Immune Checkpoint: Adenosine in Tumor Microenvironment
Within tumors, some areas are less oxygenated than others. Since their home ground is under chronic hypoxia, tumor cells adapt to this condition by activating aerobic glycolysis; however, this hypoxic environment is very harsh for incoming immune cells. Deprivation of oxygen limits availability of e...
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| Udgivet i: | Front Immunol |
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| Hovedforfatter: | |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Frontiers Media S.A.
2016
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4809887/ https://ncbi.nlm.nih.gov/pubmed/27066002 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2016.00109 |
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