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The development and immunosuppressive functions of CD4(+) CD25(+) FoxP3(+) regulatory T cells are under influence of the adenosine-A2A adenosine receptor pathway

The A2A adenosine receptor (A2AR)-mediated immunosuppression is firmly implicated in the life-saving down-regulation of collateral tissue damage during the anti-pathogen immune response and in highly undesirable protection of cancerous tissues during anti-tumor immune response. Therefore, depending...

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Detalhes bibliográficos
Main Authors: Ohta, Akio, Kini, Radhika, Ohta, Akiko, Subramanian, Meenakshi, Madasu, Manasa, Sitkovsky, Michail
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3389649/
https://ncbi.nlm.nih.gov/pubmed/22783261
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2012.00190
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