Loading...

Noncanonical PAR3 activation by factor Xa identifies a novel pathway for Tie2 activation and stabilization of vascular integrity

Endothelial barrier protective effects of activated protein C (APC) require the endothelial protein C receptor (EPCR), protease-activated receptor (PAR) 1, and PAR3. In contrast, PAR1 and PAR3 activation by thrombin results in barrier disruption. Noncanonical PAR1 and PAR3 activation by APC vs canon...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Blood
Main Authors: Stavenuiter, Fabian, Mosnier, Laurent O.
Format: Artigo
Sprog:Inglês
Udgivet: American Society of Hematology 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4246042/
https://ncbi.nlm.nih.gov/pubmed/25320242
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2014-06-582775
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!