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Prothrombotic skeletal muscle myosin directly enhances prothrombin activation by binding factors Xa and Va

To test the hypothesis that skeletal muscle myosins can directly influence blood coagulation and thrombosis, ex vivo studies of the effects of myosin on thrombogenesis in fresh human blood were conducted. Addition of myosin to blood augmented the thrombotic responses of human blood flowing over coll...

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Detalhes bibliográficos
Publicado no:Blood
Main Authors: Deguchi, Hiroshi, Sinha, Ranjeet K., Marchese, Patrizia, Ruggeri, Zaverio M., Zilberman-Rudenko, Jevgenia, McCarty, Owen J. T., Cohen, Mitchell J., Griffin, John H.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5054698/
https://ncbi.nlm.nih.gov/pubmed/27421960
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2016-03-707679
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