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Prothrombotic skeletal muscle myosin directly enhances prothrombin activation by binding factors Xa and Va

To test the hypothesis that skeletal muscle myosins can directly influence blood coagulation and thrombosis, ex vivo studies of the effects of myosin on thrombogenesis in fresh human blood were conducted. Addition of myosin to blood augmented the thrombotic responses of human blood flowing over coll...

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Bibliografiske detaljer
Udgivet i:Blood
Main Authors: Deguchi, Hiroshi, Sinha, Ranjeet K., Marchese, Patrizia, Ruggeri, Zaverio M., Zilberman-Rudenko, Jevgenia, McCarty, Owen J. T., Cohen, Mitchell J., Griffin, John H.
Format: Artigo
Sprog:Inglês
Udgivet: American Society of Hematology 2016
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Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5054698/
https://ncbi.nlm.nih.gov/pubmed/27421960
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2016-03-707679
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