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Molecular interaction site on procoagulant myosin for factor Xa–dependent prothrombin activation

Skeletal muscle myosin has potent procoagulant activity that is based on its ability to enhance thrombin generation due to binding coagulation factors Xa and Va and accelerating prothrombin activation. A well-studied myosin inhibitor that binds to myosin's neck region inhibits myosin-dependent...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Deguchi, Hiroshi, Guo, Zihan, Hayat, Mohammed, Pflimlin, Elsa, Lear, Sam, Shen, Weijun, Griffin, John H.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6791324/
https://ncbi.nlm.nih.gov/pubmed/31481465
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.AC119.010236
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