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ERG induces taxane resistance in castration-resistant prostate cancer

Taxanes are the only chemotherapies used to treat patients with metastatic castration-resistant prostate cancer (CRPC). Despite the initial efficacy of taxanes in treating CRPC, all patients ultimately fail due to the development of drug resistance. In this study, we show that ERG overexpression in...

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Библиографические подробности
Опубликовано в: :Nat Commun
Главные авторы: Galletti, Giuseppe, Matov, Alexandre, Beltran, Himisha, Fontugne, Jacqueline, Miguel Mosquera, Juan, Cheung, Cynthia, MacDonald, Theresa Y., Sung, Matthew, O’Toole, Sandra, Kench, James G., Suk Chae, Sung, Kimovski, Dragi, Tagawa, Scott T., Nanus, David M., Rubin, Mark A., Horvath, Lisa G., Giannakakou, Paraskevi, Rickman, David S.
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Pub. Group 2014
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4244604/
https://ncbi.nlm.nih.gov/pubmed/25420520
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms6548
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