Androgen Receptor Splice Variants Determine Taxane Sensitivity in Prostate Cancer

Prostate cancer growth depends on androgen receptor (AR) signaling. Androgen ablation therapy induces expression of constitutively active AR splice variants which drive disease progression. Taxanes are a standard of care therapy in castration-resistant prostate cancer (CRPC), however, mechanisms und...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Thadani-Mulero, Maria, Portella, Luigi, Sun, Shihua, Sung, Matthew, Matov, Alexandre, Vessella, Robert L., Corey, Eva, Nanus, David M., Plymate, Stephen R., Giannakakou, Paraskevi
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2014
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4012562/
https://ncbi.nlm.nih.gov/pubmed/24556717
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-13-2876
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