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The Link Between Androgen Receptor Splice Variants and Castration-Resistant Prostate Cancer

Resistance to the latest advanced prostate cancer therapies, including abiraterone and enzalutamide, is associated with increased expression of constitutively active androgen receptor splice variants (AR-Vs). The exact mechanism by which these therapies result in AR-Vs is unknown, but may include ge...

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Detalhes bibliográficos
Publicado no:Horm Cancer
Main Authors: Sprenger, Cynthia C. T., Plymate, Stephen R.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4308035/
https://ncbi.nlm.nih.gov/pubmed/24798453
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12672-014-0177-y
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