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Androgen Receptor Signaling and Metabolic and Cellular Plasticity During Progression to Castration Resistant Prostate Cancer

Metabolic reprogramming is associated with re/activation and antagonism of androgen receptor (AR) signaling that drives prostate cancer (PCa) progression to castration resistance, respectively. In particular, AR signaling influences the fates of citrate that uniquely characterizes normal and maligna...

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Publicat a:Front Oncol
Autors principals: Uo, Takuma, Sprenger, Cynthia C., Plymate, Stephen R.
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7581990/
https://ncbi.nlm.nih.gov/pubmed/33163409
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2020.580617
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