Castration resistance in human prostate cancer is conferred by a frequently occurring androgen receptor splice variant

Progression of prostate cancer following castration is associated with increased androgen receptor (AR) expression and signaling despite AR blockade. Recent studies suggest that these activities are due to the generation of constitutively active AR splice variants, but the mechanisms by which these...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Autori principali: Sun, Shihua, Sprenger, Cynthia C.T., Vessella, Robert L., Haugk, Kathleen, Soriano, Kathryn, Mostaghel, Elahe A., Page, Stephanie T., Coleman, Ilsa M., Nguyen, Holly M., Sun, Huiying, Nelson, Peter S., Plymate, Stephen R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Clinical Investigation 2010
Soggetti:
Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2912187/
https://ncbi.nlm.nih.gov/pubmed/20644256
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI41824
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi