ERG induces taxane resistance in castration-resistant prostate cancer

Taxanes are the only chemotherapies used to treat patients with metastatic castration-resistant prostate cancer (CRPC). Despite the initial efficacy of taxanes in treating CRPC, all patients ultimately fail due to the development of drug resistance. In this study, we show that ERG overexpression in...

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Publicado en:Nat Commun
Autores principales: Galletti, Giuseppe, Matov, Alexandre, Beltran, Himisha, Fontugne, Jacqueline, Miguel Mosquera, Juan, Cheung, Cynthia, MacDonald, Theresa Y., Sung, Matthew, O’Toole, Sandra, Kench, James G., Suk Chae, Sung, Kimovski, Dragi, Tagawa, Scott T., Nanus, David M., Rubin, Mark A., Horvath, Lisa G., Giannakakou, Paraskevi, Rickman, David S.
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Pub. Group 2014
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4244604/
https://ncbi.nlm.nih.gov/pubmed/25420520
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms6548
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