ERG induces taxane resistance in castration-resistant prostate cancer

Taxanes are the only chemotherapies used to treat patients with metastatic castration-resistant prostate cancer (CRPC). Despite the initial efficacy of taxanes in treating CRPC, all patients ultimately fail due to the development of drug resistance. In this study, we show that ERG overexpression in...

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Vydáno v:Nat Commun
Hlavní autoři: Galletti, Giuseppe, Matov, Alexandre, Beltran, Himisha, Fontugne, Jacqueline, Miguel Mosquera, Juan, Cheung, Cynthia, MacDonald, Theresa Y., Sung, Matthew, O’Toole, Sandra, Kench, James G., Suk Chae, Sung, Kimovski, Dragi, Tagawa, Scott T., Nanus, David M., Rubin, Mark A., Horvath, Lisa G., Giannakakou, Paraskevi, Rickman, David S.
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Pub. Group 2014
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4244604/
https://ncbi.nlm.nih.gov/pubmed/25420520
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms6548
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