Discovering cancer vulnerabilities using high-throughput micro-RNA screening

著者: Nikolic, Iva, Elsworth, Benjamin, Dodson, Eoin, Wu, Sunny Z., Gould, Cathryn M., Mestdagh, Pieter, Marshall, Glenn M., Horvath, Lisa G., Simpson, Kaylene J., Swarbrick, Alexander
出版年 Nucleic Acids Res (2017)

A data-driven, knowledge-based approach to biomarker discovery: application to circulating microRNA markers of colorectal cancer prognosis

著者: Vafaee, Fatemeh, Diakos, Connie, Kirschner, Michaela B., Reid, Glen, Michael, Michael Z., Horvath, Lisa G., Alinejad-Rokny, Hamid, Cheng, Zhangkai Jason, Kuncic, Zdenka, Clarke, Stephen
出版年 NPJ Syst Biol Appl (2018)

Phase 2 study of circulating microRNA biomarkers in castration-resistant prostate cancer

著者: Lin, Hui-Ming, Mahon, Kate L, Spielman, Calan, Gurney, Howard, Mallesara, Girish, Stockler, Martin R, Bastick, Patricia, Briscoe, Karen, Marx, Gavin, Swarbrick, Alexander, Horvath, Lisa G
出版年 Br J Cancer (2017)

Identification of Novel Response and Predictive Biomarkers to Hsp90 Inhibitors Through Proteomic Profiling of Patient-derived Prostate Tumor Explants

著者: Nguyen, Elizabeth V., Centenera, Margaret M., Moldovan, Max, Das, Rajdeep, Irani, Swati, Vincent, Andrew D., Chan, Howard, Horvath, Lisa G., Lynn, David J., Daly, Roger J., Butler, Lisa M.
出版年 Mol Cell Proteomics (2018)

p53 nuclear accumulation as an early indicator of lethal prostate cancer

著者: Quinn, David I., Stricker, Phillip D., Kench, James G., Grogan, Judith, Haynes, Anne-Maree, Henshall, Susan M., Grygiel, John J., Delprado, Warick, Turner, Jennifer J., Horvath, Lisa G., Mahon, Kate L.
出版年 Br J Cancer (2019)

Pharmacodynamics effects of CDK4/6 inhibitor LEE011 (ribociclib) in high-risk, localised prostate cancer: a study protocol for a randomised controlled phase II trial (LEEP study: L...

著者: Scheinberg, Tahlia, Kench, James, Stockler, Martin, Mahon, Kate L, Sebastian, Lucille, Stricker, Phillip, Joshua, Anthony M, Woo, H, Thanigasalam, Ruban, Ahmadi, Nariman, Centenera, Margaret M, Butler, Lisa M, Horvath, Lisa G
出版年 BMJ Open (2020)

Assessment of Periprostatic and Subcutaneous Adipose Tissue Lipolysis and Adipocyte Size from Men with Localized Prostate Cancer

著者: Miladinovic, Dushan, Cusick, Thomas, Mahon, Kate L., Haynes, Anne-Maree, Cortie, Colin H., Meyer, Barbara J., Stricker, Phillip D., Wittert, Gary A., Butler, Lisa M., Horvath, Lisa G., Hoy, Andrew J.
出版年 Cancers (Basel) (2020)

Resolution of Novel Pancreatic Ductal Adenocarcinoma Subtypes by Global Phosphotyrosine Profiling

著者: Humphrey, Emily S., Su, Shih-Ping, Nagrial, Adnan M., Hochgräfe, Falko, Pajic, Marina, Lehrbach, Gillian M., Parton, Robert G., Yap, Alpha S., Horvath, Lisa G., Chang, David K., Biankin, Andrew V., Wu, Jianmin, Daly, Roger J.
出版年 Mol Cell Proteomics (2016)

Clinical and genomic insights into circulating tumor DNA-based alterations across the spectrum of metastatic hormone-sensitive and castrate-resistant prostate cancer

著者: Kohli, Manish, Tan, Winston, Zheng, Tiantian, Wang, Amy, Montesinos, Carlos, Wong, Calven, Du, Pan, Jia, Shidong, Yadav, Siddhartha, Horvath, Lisa G., Mahon, Kate L., Kwan, Edmond M., Fettke, Heidi, Yu, Jianjun, Azad, Arun A.
出版年 EBioMedicine (2020)

Mutational load of the mitochondrial genome predicts pathological features and biochemical recurrence in prostate cancer

著者: Kalsbeek, Anton M.F., Chan, Eva F.K., Grogan, Judith, Petersen, Desiree C., Jaratlerdsiri, Weerachai, Gupta, Ruta, Lyons, Ruth J., Haynes, Anne Maree, Horvath, Lisa G., Kench, James G., Stricker, Phillip D., Hayes, Vanessa M.
出版年 Aging (Albany NY) (2016)

MicroRNAs as potential therapeutics to enhance chemosensitivity in advanced prostate cancer

著者: Lin, Hui-Ming, Nikolic, Iva, Yang, Jessica, Castillo, Lesley, Deng, Niantao, Chan, Chia-Ling, Yeung, Nicole K., Dodson, Eoin, Elsworth, Benjamin, Spielman, Calan, Lee, Brian Y., Boyer, Zoe, Simpson, Kaylene J., Daly, Roger J., Horvath, Lisa G., Swarbrick, Alexander
出版年 Sci Rep (2018)

Characterization of the ERG-regulated Kinome in Prostate Cancer Identifies TNIK as a Potential Therapeutic Target()()

著者: Lee, Rachel S, Zhang, Luxi, Berger, Adeline, Lawrence, Mitchell G, Song, Jiangning, Niranjan, Birunthi, Davies, Rebecca G, Lister, Natalie L, Sandhu, Shahneen K, Rubin, Mark A, Risbridger, Gail P, Taylor, Renea A, Rickman, David S, Horvath, Lisa G, Daly, Roger J
出版年 Neoplasia (2019)

ERG induces taxane resistance in castration-resistant prostate cancer

著者: Galletti, Giuseppe, Matov, Alexandre, Beltran, Himisha, Fontugne, Jacqueline, Miguel Mosquera, Juan, Cheung, Cynthia, MacDonald, Theresa Y., Sung, Matthew, O’Toole, Sandra, Kench, James G., Suk Chae, Sung, Kimovski, Dragi, Tagawa, Scott T., Nanus, David M., Rubin, Mark A., Horvath, Lisa G., Giannakakou, Paraskevi, Rickman, David S.
出版年 Nat Commun (2014)

Guidelines for whole genome bisulphite sequencing of intact and FFPET DNA on the Illumina HiSeq X Ten

著者: Nair, Shalima S., Luu, Phuc-Loi, Qu, Wenjia, Maddugoda, Madhavi, Huschtscha, Lily, Reddel, Roger, Chenevix-Trench, Georgia, Toso, Martina, Kench, James G., Horvath, Lisa G., Hayes, Vanessa M., Stricker, Phillip D., Hughes, Timothy P., White, Deborah L., Rasko, John E. J., Wong, Justin J.-L., Clark, Susan J.
出版年 Epigenetics Chromatin (2018)

An analysis of a multiple biomarker panel to better predict prostate cancer metastasis after radical prostatectomy

著者: Zhang, Alison Y., Chiam, Karen, Haupt, Ygal, Fox, Stephen, Birch, Simone, Tilley, Wayne, Butler, Lisa M., Knudsen, Karen, Comstock, Clay, Rasiah, Krishan, Grogan, Judith, Mahon, Kate L., Bianco-Miotto, Tina, Ricciardelli, Carmela, Böhm, Maret, Henshall, Susan, Delprado, Warick, Stricker, Phillip, Horvath, Lisa G., Kench, James G.
出版年 Int J Cancer (2018)

Combined Cell-free DNA and RNA Profiling of the Androgen Receptor: Clinical Utility of a Novel Multianalyte Liquid Biopsy Assay for Metastatic Prostate Cancer

著者: Fettke, Heidi, Kwan, Edmond M., Docanto, Maria M., Bukczynska, Patricia, Ng, Nicole, Graham, Lisa-Jane K., Mahon, Kate, Hauser, Christine, Tan, Winston, Wang, Xiao Hong, Zhao, Zhixin, Zheng, Tiantian, Zhou, Kemin, Du, Pan, Yu, Jianjun, Huang, Yong, Jia, Shidong, Kohli, Manish, Horvath, Lisa G., Azad, Arun A.
出版年 Eur Urol (2020)

Human DECR1 is an androgen-repressed survival factor that regulates PUFA oxidation to protect prostate tumor cells from ferroptosis

著者: Nassar, Zeyad D, Mah, Chui Yan, Dehairs, Jonas, Burvenich, Ingrid JG, Irani, Swati, Centenera, Margaret M, Helm, Madison, Shrestha, Raj K, Moldovan, Max, Don, Anthony S, Holst, Jeff, Scott, Andrew M, Horvath, Lisa G, Lynn, David J, Selth, Luke A, Hoy, Andrew J, Swinnen, Johannes V, Butler, Lisa M
出版年 eLife (2020)

Plasma Cell–Free DNA Profiling of PTEN-PI3K-AKT Pathway Aberrations in Metastatic Castration-Resistant Prostate Cancer

著者: Kwan, Edmond M., Dai, Chao, Fettke, Heidi, Hauser, Christine, Docanto, Maria M., Bukczynska, Patricia, Ng, Nicole, Foroughi, Siavash, Graham, Lisa-Jane K., Mahon, Kate, Tan, Winston, Wang, Xiaohong, Zhao, Zhixin, Zheng, Tiantian, Zhou, Kemin, Yu, Jianjun, Du, Pan, Horvath, Lisa G., Jia, Shidong, Kohli, Manish, Azad, Arun A.
出版年 JCO Precis Oncol (2021)

Acetylated histone variant H2A.Z is involved in the activation of neo-enhancers in prostate cancer

著者: Valdés-Mora, Fátima, Gould, Cathryn M., Colino-Sanguino, Yolanda, Qu, Wenjia, Song, Jenny Z., Taylor, Kylie M., Buske, Fabian A., Statham, Aaron L., Nair, Shalima S., Armstrong, Nicola J., Kench, James G., Lee, Kenneth M. L., Horvath, Lisa G., Qiu, Minru, Ilinykh, Alexei, Yeo-Teh, Nicole S., Gallego-Ortega, David, Stirzaker, Clare, Clark, Susan J.
出版年 Nat Commun (2017)

E6AP Promotes a Metastatic Phenotype in Prostate Cancer

著者: Gamell, Cristina, Bandilovska, Ivona, Gulati, Twishi, Kogan, Arielle, Lim, Syer Choon, Kovacevic, Zaklina, Takano, Elena A., Timpone, Clelia, Agupitan, Arjelle D., Litchfield, Cassandra, Blandino, Giovanni, Horvath, Lisa G., Fox, Stephen B., Williams, Scott G., Russo, Andrea, Gallo, Enzo, Paul, Piotr J., Mitchell, Catherine, Sandhu, Shahneen, Keam, Simon P., Haupt, Sue, Richardson, Des R., Haupt, Ygal
出版年 iScience (2019)