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GFP-Based Fluorescence Assay for CAG Repeat Instability in Cultured Human Cells

Trinucleotide repeats can be highly unstable, mutating far more frequently than point mutations. Repeats typically mutate by addition or loss of units of the repeat. CAG repeat expansions in humans trigger neurological diseases that include myotonic dystrophy, Huntington disease, and several spinoce...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:PLoS One
मुख्य लेखकों: Santillan, Beatriz A., Moye, Christopher, Mittelman, David, Wilson, John H.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Public Library of Science 2014
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC4244167/
https://ncbi.nlm.nih.gov/pubmed/25423602
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0113952
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