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GFP-Based Fluorescence Assay for CAG Repeat Instability in Cultured Human Cells
Trinucleotide repeats can be highly unstable, mutating far more frequently than point mutations. Repeats typically mutate by addition or loss of units of the repeat. CAG repeat expansions in humans trigger neurological diseases that include myotonic dystrophy, Huntington disease, and several spinoce...
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| Gepubliceerd in: | PLoS One |
|---|---|
| Hoofdauteurs: | , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
Public Library of Science
2014
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4244167/ https://ncbi.nlm.nih.gov/pubmed/25423602 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0113952 |
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