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GFP-Based Fluorescence Assay for CAG Repeat Instability in Cultured Human Cells
Trinucleotide repeats can be highly unstable, mutating far more frequently than point mutations. Repeats typically mutate by addition or loss of units of the repeat. CAG repeat expansions in humans trigger neurological diseases that include myotonic dystrophy, Huntington disease, and several spinoce...
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| Publicado no: | PLoS One |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4244167/ https://ncbi.nlm.nih.gov/pubmed/25423602 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0113952 |
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