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CAG·CTG repeat instability in cultured human astrocytes

Cells of the central nervous system (CNS) are prone to the devastating consequences of trinucleotide repeat (TNR) expansion. Some CNS cells, including astrocytes, show substantial TNR instability in affected individuals. Since astrocyte enrichment occurs in brain regions sensitive to neurodegenerati...

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Detalhes bibliográficos
Main Authors: Farrell, Brian T., Lahue, Robert S.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1636369/
https://ncbi.nlm.nih.gov/pubmed/16945950
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkl614
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