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Replication dependent instability at (CTG)•(CAG) repeat hairpins in human cells
Instability of (CTG)•(CAG) microsatellite trinucleotide repeat (TNR) sequences is responsible for more than one dozen neurological or neuromuscular diseases. TNR instability during DNA synthesis is thought to involve slipped strand or hairpin structures in template or nascent DNA strands, although d...
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| Autores principales: | , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2010
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2924473/ https://ncbi.nlm.nih.gov/pubmed/20676085 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchembio.416 |
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