Blocking Ligand Occupancy of the αVβ3 Integrin Inhibits the Development of Nephropathy in Diabetic Pigs

Hyperglycemia stimulates secretion of αVβ3 ligands from vascular cells, including endothelial cells, resulting in activation of the αVβ3 integrin. This study determined whether blocking ligand occupancy of αVβ3 would inhibit the development of diabetic nephropathy. Ten diabetic pigs received an F(ab...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Endocrinology
Main Authors: Maile, Laura A., Busby, Walker H., Gollahon, Katherine A., Flowers, William, Garbacik, Nikol, Garbacik, Stefani, Stewart, Kara, Nichols, Timothy, Bellinger, Dwight, Patel, Amit, Dunbar, Paul, Medlin, Matt, Clemmons, David
Formato: Artigo
Idioma:Inglês
Publicado em: Endocrine Society 2014
Assuntos:
Diabetes-Insulin-Glucagon-Gastrointestinal
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4239428/
https://ncbi.nlm.nih.gov/pubmed/25171599
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2014-1318
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados