A Monoclonal Antibody Against α(V)β(3) Integrin Inhibits Development of Atherosclerotic Lesions in Diabetic Pigs

Atherosclerotic lesions develop and progress more rapidly in diabetic patients than in nondiabetic individuals. This may be caused by accelerated lesion formation in the high-glucose environment of diabetes. Smooth muscle cells (SMCs) cultured in high glucose are more responsive to growth factors su...

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Hauptverfasser: Maile, Laura A., Busby, Walker H., Nichols, Timothy C., Bellinger, Dwight A., Merricks, Elizabeth P., Rowland, Michael, Veluvolu, Umadevi, Clemmons, David R.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3938114/
https://ncbi.nlm.nih.gov/pubmed/20371482
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.3000476
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