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Modulation of integrin antagonist signaling by ligand binding of the heparin binding domain of vitronectin to the αVβ3 integrin

The interaction between the arginine glycine and aspartic acid motif (RGD) of integrin ligands such as vitronectin and the integrin receptor αVβ3 in mediating cell attachment has been well described. Similarly, the ability of disintegrins, small RGD containing peptides, to inhibit cell attachment an...

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Bibliografiske detaljer
Main Authors: Maile, Laura A, Aday, Ariel W, Busby, Walker H, Sanghani, Ravi, Veluvolu, Umadevi, Clemmons, David R
Format: Artigo
Sprog:Inglês
Udgivet: 2008
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2659671/
https://ncbi.nlm.nih.gov/pubmed/18615592
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcb.21841
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