Blocking αVβ3 Integrin Ligand Occupancy Inhibits the Progression of Albuminuria in Diabetic Rats

This study determined if blocking ligand occupancy of the αVβ3 integrin could inhibit the pathophysiologic changes that occur in the early stages of diabetic nephropathy (DN). Diabetic rats were treated with either vehicle or a monoclonal antibody that binds the β3 subunit of the αVβ3 integrin. Afte...

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Detalles Bibliográficos
Main Authors: Maile, Laura A., Gollahon, Katherine, Wai, Christine, Dunbar, Paul, Busby, Walker, Clemmons, David
Formato: Artigo
Idioma:Inglês
Publicado: Hindawi Publishing Corporation 2014
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4217341/
https://ncbi.nlm.nih.gov/pubmed/25389530
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2014/421827
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