Blocking Ligand Occupancy of the αVβ3 Integrin Inhibits the Development of Nephropathy in Diabetic Pigs

Hyperglycemia stimulates secretion of αVβ3 ligands from vascular cells, including endothelial cells, resulting in activation of the αVβ3 integrin. This study determined whether blocking ligand occupancy of αVβ3 would inhibit the development of diabetic nephropathy. Ten diabetic pigs received an F(ab...

Descripció completa

Guardat en:
Dades bibliogràfiques
Publicat a:Endocrinology
Autors principals: Maile, Laura A., Busby, Walker H., Gollahon, Katherine A., Flowers, William, Garbacik, Nikol, Garbacik, Stefani, Stewart, Kara, Nichols, Timothy, Bellinger, Dwight, Patel, Amit, Dunbar, Paul, Medlin, Matt, Clemmons, David
Format: Artigo
Idioma:Inglês
Publicat: Endocrine Society 2014
Matèries:
Diabetes-Insulin-Glucagon-Gastrointestinal
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4239428/
https://ncbi.nlm.nih.gov/pubmed/25171599
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2014-1318
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars