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Optimizing the specificity of nucleic acid hybridization

The specific hybridization of complementary sequences is an essential property of nucleic acids, enabling diverse biological and biotechnological reactions and functions. However, the specificity of nucleic acid hybridization is compromised for long strands, except near the melting temperature. Here...

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Dades bibliogràfiques
Publicat a:Nat Chem
Autors principals: Zhang, David Yu, Chen, Sherry Xi, Yin, Peng
Format: Artigo
Idioma:Inglês
Publicat: 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4238961/
https://ncbi.nlm.nih.gov/pubmed/22354435
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchem.1246
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