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Optimizing the specificity of nucleic acid hybridization

The specific hybridization of complementary sequences is an essential property of nucleic acids, enabling diverse biological and biotechnological reactions and functions. However, the specificity of nucleic acid hybridization is compromised for long strands, except near the melting temperature. Here...

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Bibliografiske detaljer
Udgivet i:Nat Chem
Main Authors: Zhang, David Yu, Chen, Sherry Xi, Yin, Peng
Format: Artigo
Sprog:Inglês
Udgivet: 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4238961/
https://ncbi.nlm.nih.gov/pubmed/22354435
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchem.1246
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