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Modular probes for enriching and detecting complex nucleic acid sequences

Complex DNA sequences are difficult to detect and profile, but are important contributors to human health and disease. Existing hybridization probes lack the capability to selectively bind and enrich hypervariable, long or repetitive sequences. Here, we present a generalized strategy for constructin...

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Detalles Bibliográficos
Publicado en:Nat Chem
Main Authors: Wang, Juexiao Sherry, Yan, Yan Helen, Zhang, David Yu
Formato: Artigo
Idioma:Inglês
Publicado: 2017
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5788029/
https://ncbi.nlm.nih.gov/pubmed/29168489
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchem.2820
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