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Nucleic Acid Quantitation with Log–Linear Response Hybridization Probe Sets

Concentrations of different nucleic acid species in biological samples span many orders of magnitude. A real-time polymerase chain reaction maps the concentration of a target nucleic acid sequence log–linearly into cycle threshold to enable quantitation with a wide dynamic range but suffers from enz...

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Bibliographic Details
Published in:ACS Sens
Main Authors: Wu, Lucia R., Fang, John Z., Khodakov, Dmitriy, Zhang, David Yu
Format: Artigo
Language:Inglês
Published: 2020
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7872156/
https://ncbi.nlm.nih.gov/pubmed/32475109
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acssensors.0c00052
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