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Chemically modified nucleic acids as immunodetectable probes in hybridization experiments.
Guanine residues in nucleic acids can be modified by treatment with N-acetoxy-N-2-acetylaminofluorene and its 7-iodo derivative in an in vitro nonenzymatic reaction. The modified nucleic acids (ribo or deoxyribo, single or double stranded) are recognized by specific antibodies. They can be immunopre...
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| Gepubliceerd in: | Proc Natl Acad Sci U S A |
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| Hoofdauteurs: | , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
National Academy of Sciences
1984
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC345529/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6374657/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.81.11.3466 |
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