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Optimization of nucleic acid sequences.

Base sequence influences the structure, mechanics, dynamics, and interactions of nucleic acids. However, studying all possible sequences for a given fragment leads to a number of base combinations that increases exponentially with length. We present here a novel methodology based on a multi-copy app...

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Autori principali: Lafontaine, I, Lavery, R
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2000
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1300968/
https://ncbi.nlm.nih.gov/pubmed/10920002
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