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Mechanisms for enzymatic cleavage of the N-glycosidic bond in DNA
DNA glycosylases remove damaged or enzymatically modified nucleobases from DNA, thereby initiating the base excision repair (BER) pathway, which is found in all forms of life. These ubiquitous enzymes promote genomic integrity by initiating repair of mutagenic and/or cytotoxic lesions that arise con...
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| Опубликовано в: : | Org Biomol Chem |
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| Главные авторы: | , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2014
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4238931/ https://ncbi.nlm.nih.gov/pubmed/25181003 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c4ob01063a |
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