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Mechanisms for enzymatic cleavage of the N-glycosidic bond in DNA
DNA glycosylases remove damaged or enzymatically modified nucleobases from DNA, thereby initiating the base excision repair (BER) pathway, which is found in all forms of life. These ubiquitous enzymes promote genomic integrity by initiating repair of mutagenic and/or cytotoxic lesions that arise con...
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| Yayımlandı: | Org Biomol Chem |
|---|---|
| Asıl Yazarlar: | , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
2014
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4238931/ https://ncbi.nlm.nih.gov/pubmed/25181003 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c4ob01063a |
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