Llwytho...

Divergent mechanisms for enzymatic excision of 5-formylcytosine and 5-carboxylcytosine from DNA

5-methylcytosine (mC) is an epigenetic mark that impacts transcription, development, and genome stability, and aberrant DNA methylation contributes to aging and cancer. Active DNA demethylation involves stepwise oxidation of mC to 5-hydroxymethylcytosine, 5-formylcytosine (fC), and potentially 5-car...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Maiti, Atanu, Michelson, Anna Zhachkina, Armwood, Cherece J, Lee, Jeehiun K, Drohat, Alexander C
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2013
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3930231/
https://ncbi.nlm.nih.gov/pubmed/24063363
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja406444x
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