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Mechanisms for enzymatic cleavage of the N-glycosidic bond in DNA

DNA glycosylases remove damaged or enzymatically modified nucleobases from DNA, thereby initiating the base excision repair (BER) pathway, which is found in all forms of life. These ubiquitous enzymes promote genomic integrity by initiating repair of mutagenic and/or cytotoxic lesions that arise con...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Org Biomol Chem
Päätekijät: Drohat, Alexander C., Maiti, Atanu
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2014
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4238931/
https://ncbi.nlm.nih.gov/pubmed/25181003
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c4ob01063a
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