Tumor suppressive miR-148a is silenced by CpG island hypermethylation in IDH1 mutant gliomas

PURPOSE: IDH1/2 mutant gliomas harbor a distinct CpG island methylation profile (G-CIMP) that may promote the initiation and progression of secondary pathway gliomas by silencing tumor suppressive genes. The potential role of tumor suppressive miRNAs in this process is not understood. EXPERIMENTAL D...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Clin Cancer Res
Egile Nagusiak: Li, Sichen, Chowdhury, Reshmi, Liu, Fei, Chou, Arthur P., Li, Tie, Mody, Reema R., Lou, Jerry J., Chen, Weidong, Reiss, Jean, Soto, Horacio, Prins, Robert, Liau, Linda M., Mischel, Paul S., Nghiemphu, Phioanh L., Yong, William H., Cloughesy, Timothy F., Lai, Albert
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2014
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4233178/
https://ncbi.nlm.nih.gov/pubmed/25224277
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-14-0234
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