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Tumor suppressive miR-148a is silenced by CpG island hypermethylation in IDH1 mutant gliomas
PURPOSE: IDH1/2 mutant gliomas harbor a distinct CpG island methylation profile (G-CIMP) that may promote the initiation and progression of secondary pathway gliomas by silencing tumor suppressive genes. The potential role of tumor suppressive miRNAs in this process is not understood. EXPERIMENTAL D...
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| 出版年: | Clin Cancer Res |
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| 主要な著者: | , , , , , , , , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2014
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4233178/ https://ncbi.nlm.nih.gov/pubmed/25224277 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-14-0234 |
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