Tumor suppressive miR-148a is silenced by CpG island hypermethylation in IDH1 mutant gliomas

PURPOSE: IDH1/2 mutant gliomas harbor a distinct CpG island methylation profile (G-CIMP) that may promote the initiation and progression of secondary pathway gliomas by silencing tumor suppressive genes. The potential role of tumor suppressive miRNAs in this process is not understood. EXPERIMENTAL D...

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Detaylı Bibliyografya
Yayımlandı:Clin Cancer Res
Asıl Yazarlar: Li, Sichen, Chowdhury, Reshmi, Liu, Fei, Chou, Arthur P., Li, Tie, Mody, Reema R., Lou, Jerry J., Chen, Weidong, Reiss, Jean, Soto, Horacio, Prins, Robert, Liau, Linda M., Mischel, Paul S., Nghiemphu, Phioanh L., Yong, William H., Cloughesy, Timothy F., Lai, Albert
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2014
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4233178/
https://ncbi.nlm.nih.gov/pubmed/25224277
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-14-0234
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