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Activating and propagating polyclonal gamma delta T cells with broad specificity for malignancies
PURPOSE: To activate and propagate populations of γδT cells expressing polyclonal repertoire of γ and δ TCR chains for adoptive immunotherapy for cancer, which has yet to be achieved. EXPERIMENTAL DESIGN: Clinical-grade artificial antigen presenting cells (aAPC) derived from K562 tumor cells were us...
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Pubblicato in: | Clin Cancer Res |
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Autori principali: | , , , , , , , , , , , , , |
Natura: | Artigo |
Lingua: | Inglês |
Pubblicazione: |
2014
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Soggetti: | |
Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4233015/ https://ncbi.nlm.nih.gov/pubmed/24833662 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-13-3451 |
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